amd

AMD MI300A

CDNA 3–based accelerated processing unit combining CPU and GPU for tightly coupled AI and HPC workloads.

Release

2024

GPU Class

ata Center APU / AI & HPC Accelerator

Architecture

MD CDNA 3 (GPU) + Zen 4 (CPU)

PRICE SNAPSHOT

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On-premise Module

~$30k–$40k

Turnkey System

~$250k–$400k+

Cloud Pricing
(per GPU/hr)

~$4.00–$12+/hr

chip identity

GPU-amd-instinct-mi300a-product 1

On-premise Module

MI300A

GPU Class

ata Center APU / AI & HPC Accelerator

Release

2024

Architecture

MD CDNA 3 (GPU) + Zen 4 (CPU)

Target Workload

  • HPC and AI workloads requiring tight CPU–GPU coupling
  • Large-scale scientific simulations and modeling
  • AI training and inference pipelines with heavy CPU preprocessing
  • Unified-memory workloads sensitive to data movement overhead

Compatible Platforms

  • OEM server platforms integrating MI300A APUs
  • Supercomputing and HPC cluster deployments
  • Custom AI and HPC systems via OEM and system integrators
  • Interconnect: Infinity Fabric (on-package CPU–GPU coherence; system-level scale-out via high-speed networking)
  • Software Stack: ROCm, HIP, OpenMP, MPI, PyTorch (ROCm), HPC scientific libraries

Ideal Buyer Profile

Enterprises and institutions requiring:

  • Tight CPU–GPU integration with shared memory
  • High performance for hybrid AI and HPC workloads
  • Simplified programming models for complex simulations
  • Large-scale, tightly coupled system deployments

Typical adopters include national laboratories, research institutions, and organizations building next-generation supercomputers or advanced AI/HPC clusters.

Availability Notes

MI300A is available through OEM partners and system integrators, primarily as part of complete server or supercomputing platforms rather than as a standalone retail component. Deployments are often tied to large-scale contracts and specialized system designs, with availability varying by region and program.

Recent Developments

  • Late 2023 β€” AMD introduces MI300A as part of the Instinct MI300 family, highlighting unified CPU–GPU memory.
  • 2024 β€” MI300A enters production deployment in large-scale HPC systems and research clusters.
  • 2025 β€” Software ecosystem enhancements in ROCm improve unified-memory support and AI framework compatibility.

overview

The AMD Instinct MI300A is a CDNA 3–generation accelerated processing unit that integrates high-performance Zen 4 CPU cores and a CDNA 3 GPU into a single coherent package. Unlike discrete accelerators, MI300A is designed to minimize data movement between CPU and GPU by providing a shared memory space, reducing latency and improving efficiency for tightly coupled AI and HPC workloads.

MI300A is primarily deployed in large-scale HPC systems and advanced AI platforms where CPU–GPU coordination is critical. It serves as a foundational component in next-generation supercomputers and research clusters, enabling unified-memory programming models and improved performance for simulations, modeling, and AI workloads that combine heavy CPU logic with GPU acceleration.

Key specifications

Specification MI300A APU
Architecture AMD CDNAΒ 3 (GPU) + ZenΒ 4 (CPU)
CPU Cores 24Β ZenΒ 4 cores
Memory 128Β GB HBM3 (shared CPU–GPU)
Memory Bandwidth ~5.2Β TB/s
Interconnect Infinity Fabric (coherent CPU–GPU on-package links)
Form Factor OAM module
Max TGP ~750Β W
Precision Support FP64, FP32, FP16, BF16, FP8, INT8
Typical AI Compute Not publicly standardized (workload- and precision-dependent)
Process Node TSMCΒ 5Β nm and 6Β nm chiplets
Transistor Count ~146Β billion
MIG Support Not supported (relies on OS-level and software partitioning)
NVLink (peer) Not supported

Performance Summary

  • AI/ML Throughput: Designed to deliver strong mixed-precision AI performance while reducing CPU–GPU communication overhead; benefits are most pronounced in workflows that alternate frequently between CPU and GPU execution.
  • Compute Architecture: Combines Zen 4 CPU cores with CDNA 3 matrix engines, enabling efficient execution of hybrid AI and HPC workloads within a unified programming model.
  • Memory Bandwidth: Shared HBM3 memory with very high bandwidth (~5.2 TB/s) reduces data duplication and memory transfer penalties common in discrete CPU–GPU systems.
  • Scale-Out Behavior: MI300A scales primarily at the system and cluster level using high-speed networking rather than GPU-to-GPU fabrics, favoring workloads that parallelize across nodes.

Compared to discrete accelerators such as MI300X or NVIDIA H100, MI300A prioritizes data locality and unified memory over peak standalone GPU throughput, making it particularly effective for tightly coupled workloads.

primary use case

  • HPC simulations and scientific computing requiring frequent CPU–GPU data exchange
  • AI workloads with heavy preprocessing or control logic on the CPU
  • Hybrid AI/HPC pipelines combining modeling, simulation, and machine learning
  • Unified-memory applications sensitive to data transfer latency
  • Large-scale research and supercomputing deployments

Alternatives & Upgrade Path

Comparable Accelerators:

  • AMD Instinct MI300X: Discrete GPU variant optimized for high-memory AI inference and training.
  • NVIDIA GH200 Grace Hopper: CPU–GPU superchip offering a competing coherent-memory approach.
  • NVIDIA H100: Discrete GPU favored when peak tensor throughput and NVLink scale-up are priorities.

Organizations already invested in MI300A typically view MI300X or future CDNA-based APUs as upgrade paths, while those prioritizing discrete GPU performance may evaluate NVIDIA alternatives.

Enterprises and institutions requiring:

  • Tight CPU–GPU integration with shared memory
  • High performance for hybrid AI and HPC workloads
  • Simplified programming models for complex simulations
  • Large-scale, tightly coupled system deployments

Typical adopters include national laboratories, research institutions, and organizations building next-generation supercomputers or advanced AI/HPC clusters.

Related Chips & Providers

Related AMD Accelerators:

  • Instinct MI300X
  • Instinct MI250X

Competitor Accelerators:

  • NVIDIA GH200 Grace Hopper
  • NVIDIA H100

SUMMARY

The AMD Instinct MI300A is a CDNA 3–based APU designed to tightly integrate CPU and GPU compute with a shared high-bandwidth memory pool. By minimizing data movement and enabling unified-memory programming, it excels in hybrid AI and HPC workloads that require close coordination between CPU and GPU execution. MI300A is primarily deployed in large-scale research and supercomputing environments, serving as a specialized alternative to discrete accelerators where data locality and system-level efficiency are more critical than peak standalone GPU throughput.

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